Early Stage Investigators and Multi-PI R01 Grants

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NIH implemented multiple principal investigator (MPI) grants starting in 2007 to support projects led by teams of principal investigators (PIs) who have shared responsibility and are each named as a PI for the award. Although the MPI arrangement can be effective in enabling single-grant supported projects for integrated teams working on common sets of goals, it isn’t the optimal approach for many collaborative projects and can pose challenges in some circumstances. For example, if an early stage investigator (ESI) joins an MPI R01 or other MPI major research grant, there may be unintended consequences such as the following: 

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IPERT R25 Funding Opportunity and Upcoming Webinar

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UPDATE: The video and slides [PDF] from this webinar are available.

We’re pleased to announce that the notice of funding opportunity (NOFO) for the Innovative Programs to Enhance Research Training (IPERT) has been reissued (PAR-24-252). IPERT supports innovative educational activities that equip participants at various career stages with the skills required for careers in the biomedical research workforce. NIGMS prioritizes programs that are open to participants nationwide.

First application due date: October 17, 2024
Earliest start date: July 2025

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New MOSAIC Funding Opportunities and Upcoming Webinar

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UPDATE: The video and slides [PDF] from this webinar are now available.

We’re pleased to share that the Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) notices of funding opportunities (NOFOs) have been reissued. MOSAIC, an NIH-wide initiative that NIGMS oversees, has two components: a postdoctoral career transition award (K99/R00) and a cohort-based mentoring and career development program that supports the scholars (UE5 research education cooperative agreement).

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New Bridges to the Doctorate Funding Opportunity and Upcoming Webinar

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UPDATE: The video and slides [PDF] from this webinar are now available.

We’re pleased to announce that the notice of funding opportunity (NOFO) for the Bridges to the Doctorate (B2D) program has been reissued (PAR-24-232). This NOFO aims to promote broad participation in the biomedical research workforce by strengthening research training environments and expanding the pool of well-trained master’s students who transition into and complete biomedical Ph.D.s. NIGMS expects organizations to engage in outreach and recruitment activities to encourage individuals from underrepresented groups to participate in this program.

First application due date: September 27, 2024
Earliest start date: August 2025

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Virtual Office Hour for Bridges to the Baccalaureate Program Applicants

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UPDATE: The slides [PDF] for this office hour are now available.

We’re pleased to announce a virtual “office hour” on Thursday, August 1, for the Bridges to the Baccalaureate (B2B) Research Training Program (PAR-22-125).

B2B develops a diverse pool of research-oriented undergraduates who transition from associate to baccalaureate degree-granting institutions and complete a baccalaureate STEM degree, positioning them to pursue research-oriented biomedical higher degree programs or enter careers in the biomedical research workforce.

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Funding Opportunity: Research on Behavioral Interventions That Promote Careers in the Biomedical Research Enterprise

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We’re pleased to announce that our Research on Interventions That Promote the Careers of Individuals in the Biomedical Research Enterprise notice of funding opportunity (NOFO) has been reissued under a new name: B-INSPIRE, short for Research on Behavioral INterventionS That Promote Careers In the Biomedical Research Enterprise (R01) (PAR-24-230). The new name better reflects the goal of this program: to test theoretically based behavioral interventions that enhance research-oriented individuals’ interest, motivation, persistence, and preparedness for careers in the biomedical research workforce.

Applicants must propose an intervention that tests effectiveness using robust experimental designs, such as randomized control trial approaches, case controls, or matched pair design, appropriate to performing rigorous research on effective interventions aiming to increase success in the biomedical research workforce. Possible areas for the intervention include but are not limited to training, mentoring, and networking; navigating critical transition points; institutional factors that influence persistence; harassment; and barriers to participation. The intervention should be cost-effective, practical, realistic, scalable, and sustainable at a broad range of institutions.

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New NIGMS Resource: Trainee Feedback Form

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We’re pleased to announce the creation of an online form for trainees to share feedback on NIGMS research education, training, and career development programs. We value this input as NIGMS refines its existing programs and develops new opportunities to meet emerging needs in biomedical research training.

The form, which can be completed anonymously, allows trainees to submit constructive comments—for example, to suggest program improvements or to recognize an outstanding program for its training and mentorship activities. NIGMS welcomes submissions from trainees across all educational and career stages.

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Wanted: Division of Training, Workforce Development, and Diversity Director

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TWD Search Committee Members:

Shawn Drew Gaillard, National Institute of General Medical Sciences, NIH, Chair

Oliver Bogler, National Cancer Institute, NIH

Ericka Boone, Office of Extramural Research, NIH

Luis Cubano, National Science Foundation

Terri Kinzy, Rutgers University

Pamela Stacks, San Jose State University

Danny Dickerson, Office of Equity, Diversity, and Inclusion, NIH

Laura Stanek, Office of Human Resources, NIH

With the impending retirement of Alison Gammie, a search is open for an outstanding candidate to serve as director of our Division of Training, Workforce Development, and Diversity (TWD).

TWD supports programs that foster the development of a strong and diverse biomedical research workforce. The Division funds research training, student development, and career development activities through a variety of programs ranging from the undergraduate level to the doctorate and beyond. TWD-funded initiatives include, among others, the Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) and the Advancing Research Careers (ARC) programs.

This position offers an exciting opportunity to set scientific priorities, lead change, and enhance the biomedical research enterprise. The TWD director is a key member of the NIGMS senior leadership team and supervises a staff of approximately 12 program officers. There are also opportunities to participate in and advise on HHS- and NIH-wide activities and collaborations with other federal agencies.

Candidates must have earned a Ph.D., M.D., or equivalent degree in a field related to the Division portfolio. The ideal candidate will have considerable research experience and/or research administration experience. In addition, candidates should have professional experience with programs aimed to train research scientists and to develop a diverse biomedical and behavioral research workforce, as well as knowledge related to the NIGMS mission.

For additional information and application instructions, please visit the vacancy announcement. NIGMS will accept applications for at least 45 days, beginning on June 18, and the application period will remain open until filled.

As chair of the search committee, I appreciate your help in identifying outstanding candidates for this critical position and in sharing this information with others who might be interested.

Request for Information: Mature Synchrotron Resources for Structural Biology Program Evaluation

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NIGMS supports a variety of structural biology research resources, including those funded through the Mature Synchrotron Resources (MSR) program. We’re currently evaluating the MSR program to inform future directions about the structure and operations of the program. As part of this evaluation, we’re seeking input from the extramural community (e.g., principal investigators and key personnel of MSR awards, resource staff, the user community, members of relevant advisory boards, and any other interested parties) on their experiences with and/or opinions on NIGMS-supported synchrotron resources.

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Wanted: Tribal Health Research Strategy Coordinator

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UPDATE: This position is now open and will close on May 22. Direct links to these vacancy announcements and more information about this position are available on our job vacancies webpage.

We’re recruiting an outstanding individual to serve as the NIGMS Tribal health research strategy coordinator. The incumbent will report to the deputy director and assume a broad sphere of responsibilities that include, among others:

  • Serving as the expert on matters related to Tribal health research within the NIGMS mission, and as a resource for the Institute director, deputy director, our associate director for extramural activities, and other senior leadership within NIGMS
  • Serving as a senior-level NIGMS representative in collaborations and initiatives with the NIH Tribal Health Research Office, the Indian Health Service, Tribal nations, and federal and academic partners across the country
  • Formulating, planning, directing, and evaluating broad NIGMS-wide program objectives, policies, and activities for Tribal health research projects, programs, and other grants/awards including the discovery, development, and evaluation of scientific areas critical for eventual prevention and therapeutic strategies
  • Advising leadership on strategies to address ongoing matters with Tribal communities
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