(Q28589335)

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Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence

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scholarly article

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PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence (English)

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Pantothenate kinase 1

1 reference

GOA release 2020-03-11

Protein tyrosine phosphatase, receptor type, C

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

CD8 antigen, alpha chain

1 reference

GOA release 2020-03-11

Forkhead box N1

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Placenta expressed transcript 1

1 reference

GOA release 2020-03-11

Interleukin 2 receptor, alpha chain

1 reference

GOA release 2020-03-11

Julie M Sheridan

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Clare Blackburn

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Nicholas Bredenkamp

2

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Stéphanie Tetélin

3

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Xin Jin

4

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Christin Tischner

5

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Harsh Vaidya

6

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Frances Hogg Stenhouse

8

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Raphaela Heussen

9

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Craig S Nowell

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Andrew J H Smith

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

publication date

3 November 2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

7

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

11

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

e1002348

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

copyright license

Creative Commons Attribution 4.0 International

3 November 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Foxn1 is essential for vascularization of the murine thymus anlage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

The emerging roles of forkhead box (Fox) proteins in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Regulation of CD8+ T cell development by thymus-specific proteasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Role of the nude gene in epithelial terminal differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

The role of Hoxa-3 in mouse thymus and thyroid development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

17 March 2017

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Dedicated epithelial recipient cells determine pigmentation patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Thymus medulla consisting of epithelial islets each derived from a single progenitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Housekeeping genes as internal standards: use and limits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Targeted expression of SV40 large T-antigen to visceral smooth muscle induces proliferation of contractile smooth muscle cells and results in megacolon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

MAZ-dependent termination between closely spaced human complement genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Heterogeneity of thymic epithelial cells in promoting T-lymphocyte differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

29 September 2017

Delta-like 4 is indispensable in thymic environment specific for T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

3 June 2018

Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

3 June 2018

The phenotypic heterogeneity of mouse thymic stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

3 June 2018

Nude Mouse Embryo: Ectodermal Nature of the Primordial Thymic Defect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

3 June 2018

Functional evidence for a single endodermal origin for the thymic epithelium.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Identification of molecular markers that are expressed in discrete anterior-posterior domains of the endoderm from the gastrula stage to mid-gestation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Formation of a functional thymus initiated by a postnatal epithelial progenitor cell.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Exposing the human nude phenotype

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

EVA regulates thymic stromal organisation and early thymocyte development.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Two genetically separable steps in the differentiation of thymic epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

27 November 2018

Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207875

27 November 2018

Absence of Thymus in a Mouse Mutant

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002348

21 January 2018

Identification of a tandem duplicated array in the Rhox α locus on mouse chromosome X

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An epithelial progenitor pool regulates thymus growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Checkpoints in the development of thymic cortical epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbiased analysis, enrichment and purification of thymic stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA cloning by homologous recombination in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two distinct steps of immigration of hematopoietic progenitors into the early thymus anlage

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and Characterization of Thymic Epithelial Progenitor Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Dll4 and CCL25 in Foxn1-negative epithelial cells in the post-natal thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

‘Nude’, a new hairless gene with pleiotropic effects in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of mouse CD40: differential expression of CD40 epitopes on dendritic cells and epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Delta like 1 and 4 expressions in nude thymus anlages

1 reference

https://pubmed.ncbi.nlm.nih.gov/22072979

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1002348

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22072979%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

ResearchGate publication ID

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