(Q36371509)

English

Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

scientific article published on November 17, 2003

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells (English)

1 reference

10.1084/JEM.20030874

https://api.crossref.org/works/10.1084/JEM.20030874

3 April 2024

0 references

cell cycle proteins

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

1 reference

10.1084/JEM.20030874

https://api.crossref.org/works/10.1084/JEM.20030874

3 April 2024

11

object named as

Joan Brugge

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Keiko Fujikawa

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Roberta Faccio

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Tracie Brown

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jeremy Hoog

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jessica Fredericks

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Shinzo Nishi

8

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Shirly Mildiner

9

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wojciech Swat

13

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ana V. Miletic

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

Frederick W. Alt

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

Sheri L. Moores

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

Fred S. Rosen

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

language of work or name

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publication date

1 November 2003

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Europe PubMed Central

PMC publication ID

13 August 2017

17 November 2003

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14623913

3 April 2024

full work available at URL

https://rupress.org/jem/article-pdf/198/10/1595/1710601/jem198101595.pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

https://europepmc.org/articles/PMC2194126

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

https://europepmc.org/articles/PMC2194126?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623913

3 April 2024

https://rupress.org/jem/article-pdf/198/10/1595/1710601/jem198101595.pdf

Portable Document Format

1 reference

10.1084/JEM.20030874

https://api.crossref.org/works/10.1084/JEM.20030874

3 April 2024

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

198

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1595-1608

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2194126/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

B cell antigen receptor signaling: roles in cell development and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Vav3 is regulated during the cell cycle and effects cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Positive and negative regulation of T-cell activation by adaptor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

On the brink of becoming a T cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Vav proteins, adaptors and cell signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Vav-2 controls NFAT-dependent transcription in B- but not T-lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

B-cell activation 2000.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Vav family proteins couple to diverse cell surface receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

T cell activation and the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Signal transduction by the TCR for antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Control of B cell development by Ras-mediated activation of Raf.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

30 September 2017

Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

28 June 2018

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194126

28 June 2018

The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Disruption of T cell signaling networks and development by Grb2 haploid insufficiency.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Essential role for Vav1 in activation, but not development, of gammadelta T cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

Defective immunoglobulin class switching in Vav-deficient mice is attributable to compromised T cell help

2 references

https://api.crossref.org/works/10.1084%2FJEM.20030874

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/14623913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nature Immunology

6

2

403

publication date

2001

1 reference

10.1084/JEM.20030874

https://api.crossref.org/works/10.1084/JEM.20030874

3 April 2024

Identifiers

10.1084/JEM.20030874

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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