4-Amino-6-benzylamino-1,2-dihydro-2-phenyl-1,2,4-triazolo [4,3-alpha]-quinoxalin-1-one: a new A2A adenosine receptor antagonist with high selectivity versus A1 receptors

Arch Pharm (Weinheim). 1999 Feb;332(2):39-41. doi: 10.1002/(sici)1521-4184(19993)332:2<39::aid-ardp39>3.0.co;2-f.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Binding Sites
  • Cattle
  • Purinergic P1 Receptor Antagonists*
  • Pyrimidines / metabolism
  • Pyrimidines / pharmacology
  • Quinoxalines / chemical synthesis*
  • Quinoxalines / metabolism
  • Quinoxalines / pharmacology
  • Receptor, Adenosine A2A
  • Receptors, Purinergic P1 / metabolism
  • Structure-Activity Relationship
  • Triazoles / chemical synthesis*
  • Triazoles / metabolism
  • Triazoles / pharmacology

Substances

  • 4-amino-6-benzylamino-1,2-dihydro-2-phenyl-1,2,4-triazolo(4,3-a)-quinoxalin-1-one
  • 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine
  • Purinergic P1 Receptor Antagonists
  • Pyrimidines
  • Quinoxalines
  • Receptor, Adenosine A2A
  • Receptors, Purinergic P1
  • Triazoles