3-Hydroxyglutaric and glutaric acids are neurotoxic through NMDA receptors in vitro

J Inherit Metab Dis. 1999 May;22(3):259-62. doi: 10.1023/a:1005577920954.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Survival / drug effects
  • Cells, Cultured
  • Chick Embryo
  • Excitatory Amino Acid Antagonists / pharmacology
  • Glutarates / metabolism*
  • Glutarates / pharmacology
  • Glutarates / toxicity
  • Neurons / drug effects*
  • Neurons / metabolism
  • Receptors, N-Methyl-D-Aspartate / metabolism*

Substances

  • 3-hydroxyglutaric acid
  • Excitatory Amino Acid Antagonists
  • Glutarates
  • Receptors, N-Methyl-D-Aspartate
  • glutaric acid