Reactivation of scabies rash by methotrexate

Br J Dermatol. 1975 Aug;93(2):219-21.

Abstract

A 13-year-old female was on maintenance therapy for acute lymphoblastic leukemia. On three occasions she received methotrexate orally and each time this was associated with reactivation of scabies rash. The mechanisms for this phenomenon are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Benzyl Compounds / therapeutic use
  • Cytarabine / therapeutic use
  • Female
  • Humans
  • Leukemia, Lymphoid / complications
  • Leukemia, Lymphoid / drug therapy
  • Mercaptopurine / therapeutic use
  • Methotrexate / adverse effects*
  • Methotrexate / therapeutic use
  • Prednisolone / therapeutic use
  • Remission, Spontaneous
  • Scabies / chemically induced*
  • Scabies / drug therapy
  • Vincristine / therapeutic use

Substances

  • Benzyl Compounds
  • Cytarabine
  • Vincristine
  • Prednisolone
  • Mercaptopurine
  • Methotrexate