Cyclooxygenase-independent induction of p21WAF-1/CIP1, apoptosis and differentiation by L-745,337 and salicylate in HT-29 colon cancer cells

Adv Exp Med Biol. 1999:469:555-61. doi: 10.1007/978-1-4615-4793-8_81.
No abstract available

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Apoptosis / drug effects*
  • Apoptosis / physiology
  • Cell Differentiation / drug effects*
  • Cell Differentiation / physiology
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclins / biosynthesis*
  • Cyclooxygenase 1
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / pharmacology
  • HT29 Cells
  • Humans
  • Indans / pharmacology*
  • Isoenzymes / metabolism
  • Membrane Proteins
  • Prostaglandin-Endoperoxide Synthases / metabolism*
  • Salicylic Acid / pharmacology*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • CDKN1A protein, human
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclins
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Indans
  • Isoenzymes
  • L 745337
  • Membrane Proteins
  • Cyclooxygenase 1
  • Cyclooxygenase 2
  • PTGS1 protein, human
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases
  • Salicylic Acid