Abstract
The paper reviews the factors which affect synthesis and metabolic activity of the insulin-like growth factor-I (IGF-I), its receptor and binding proteins as age, nutritional state, hormonal state and liver function. Attention is also focused on the role of IGF-I in pathogenesis of osteoporosis and neoplastic diseases.
Publication types
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Editorial
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English Abstract
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Review
MeSH terms
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Humans
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Insulin-Like Growth Factor I / metabolism*
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Liver Diseases / metabolism
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Liver Function Tests
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Neoplasms / metabolism
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Nutritional Status
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Osteoporosis / metabolism
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Receptor, IGF Type 1 / metabolism
Substances
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Insulin-Like Growth Factor I
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Receptor, IGF Type 1