SOX8 expression during chick embryogenesis

K M Bell; P S Western; A H Sinclair

doi:10.1016/s0925-4773(00)00296-3

SOX8 expression during chick embryogenesis

Mech Dev. 2000 Jun;94(1-2):257-60. doi: 10.1016/s0925-4773(00)00296-3.

Authors

K M Bell¹, P S Western, A H Sinclair

Affiliation

¹ Department of Pediatrics, Centre for Hormone Research, University of Melbourne, Royal Children's Hospital, Australia.

PMID: 10842083
DOI: 10.1016/s0925-4773(00)00296-3

Abstract

We have isolated the SOX8 gene from the chicken embryo. This gene shows a high degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX8 expression by whole-mount in situ shows a dynamic and restricted expression pattern during chick development. SOX8 is expressed in the somitic derivative, the dermomyotome, the developing heart, pancreas, enteric neurone system, limb and the neural tube. This is the first detailed expression analysis of SOX8 in any species

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Chick Embryo
DNA-Binding Proteins / genetics*
DNA-Binding Proteins / metabolism
Extremities / embryology
Gene Expression Regulation, Developmental*
Molecular Sequence Data
Muscle, Skeletal / embryology
Pancreas / embryology
Sequence Homology, Amino Acid
Transcription Factors / genetics*
Transcription Factors / metabolism

Substances

DNA-Binding Proteins
Transcription Factors

Associated data

GENBANK/AF228664