Abstract
Photodynamic therapy seems to be able to control high-grade dysplasia within Barrett's esophagus about 80% of the time. Long-term results are not available, but the treatment is promising. Given the success with surgical intervention, however, use of photodynamic therapy should be reserved for nonsurgical candidates at the current time. The complications that occur with photodynamic therapy are not trivial and must be weighed against the potential benefits.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Aminolevulinic Acid / administration & dosage
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Aminolevulinic Acid / therapeutic use
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Barrett Esophagus / drug therapy*
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Esophagoscopy
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Fiber Optic Technology
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Hematoporphyrin Derivative / administration & dosage
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Hematoporphyrin Derivative / therapeutic use
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Humans
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Injections, Intravenous
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Laser Therapy
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Photochemotherapy* / methods
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Photosensitizing Agents / administration & dosage
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Photosensitizing Agents / therapeutic use*
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Protoporphyrins / administration & dosage
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Protoporphyrins / therapeutic use
Substances
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Photosensitizing Agents
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Protoporphyrins
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Hematoporphyrin Derivative
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Aminolevulinic Acid
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protoporphyrin IX