Breast biphasic compression (22.5 degrees angled paddle, followed by progressive angle reduction) was compared with standard monophasic compression in x-ray mammography. The presence of the pectoral muscle was recorded for the craniocaudal (CC) view and the presence of the inframammary fold for the mediolateral oblique (MLO) view. The amount of breast in each study and image quality were assessed for both views. For all parameters, biphasic compression performed better than monophasic compression in both CC (P: <.006) and MLO (P: <.04) views.