Drug-resistant parasites and aggregated infection--early-season dynamics

J Math Biol. 2000 Oct;41(4):341-60. doi: 10.1007/s002850000051.

Abstract

We investigate the effect of spatial aggregation in the infection dynamics of nematode parasites in ruminants. We show that a high degree of spatial aggregation is likely to lead to a dramatically enhanced rate of invasion by drug-resistant strains.

MeSH terms

  • Animals
  • Anthelmintics / pharmacology*
  • Drug Resistance / genetics
  • Female
  • Humans
  • Male
  • Mathematics
  • Models, Biological*
  • Nematoda / drug effects
  • Nematoda / genetics
  • Nematode Infections / drug therapy*
  • Nematode Infections / parasitology*
  • Nematode Infections / veterinary
  • Sheep
  • Sheep Diseases / drug therapy
  • Sheep Diseases / parasitology

Substances

  • Anthelmintics