Aberrant regeneration of the third nerve

Singapore Med J. 2000 Sep;41(9):458-9.

Abstract

We describe three patients with aberrant regeneration of the third nerve secondary to traumatic brain injury. The full blown features of the syndrome include horizontal gaze-eyelid synkinesis, pseudo-Graefe sign, limitation of elevation and depression of the eye with retraction of the globe on attempted vertical movements, adduction of the involved eye on attempted elevation or depression, pseudo-Argyll Robertson pupil and absent vertical optokinetic response. The 'misdirection' incidence in our study is 15%.

MeSH terms

  • Adult
  • Brain Injuries / complications*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Ocular Motility Disorders / etiology
  • Oculomotor Nerve / growth & development*
  • Oculomotor Nerve / pathology
  • Oculomotor Nerve Diseases / etiology
  • Oculomotor Nerve Diseases / pathology*
  • Pregnancy
  • Pupil Disorders / etiology
  • Pupil Disorders / pathology