Werner syndrome cells are sensitive to DNA cross-linking drugs

FASEB J. 2001 May;15(7):1224-6. doi: 10.1096/fj.00-0611fje.
No abstract available

MeSH terms

  • Antineoplastic Agents / pharmacology
  • Apoptosis
  • Cell Cycle / drug effects
  • Cell Cycle / physiology
  • Cell Line
  • Cross-Linking Reagents / pharmacology*
  • DNA / metabolism*
  • DNA Helicases / genetics
  • DNA Helicases / metabolism*
  • Enzyme Inhibitors / pharmacology
  • Exodeoxyribonucleases
  • Humans
  • Intercalating Agents / pharmacology*
  • Lymphocytes / drug effects*
  • Lymphocytes / pathology
  • RecQ Helicases
  • Werner Syndrome / genetics
  • Werner Syndrome / pathology*
  • Werner Syndrome Helicase

Substances

  • Antineoplastic Agents
  • Cross-Linking Reagents
  • Enzyme Inhibitors
  • Intercalating Agents
  • DNA
  • Exodeoxyribonucleases
  • DNA Helicases
  • RecQ Helicases
  • WRN protein, human
  • Werner Syndrome Helicase