Monitoring the expression profiles of 7000 Arabidopsis genes under drought, cold and high-salinity stresses using a full-length cDNA microarray

Plant J. 2002 Aug;31(3):279-92. doi: 10.1046/j.1365-313x.2002.01359.x.

Abstract

Full-length cDNAs are essential for functional analysis of plant genes in the post-sequencing era of the Arabidopsis genome. Recently, cDNA microarray analysis has been developed for quantitative analysis of global and simultaneous analysis of expression profiles. We have prepared a full-length cDNA microarray containing approximately 7000 independent, full-length cDNA groups to analyse the expression profiles of genes under drought, cold (low temperature) and high-salinity stress conditions over time. The transcripts of 53, 277 and 194 genes increased after cold, drought and high-salinity treatments, respectively, more than fivefold compared with the control genes. We also identified many highly drought-, cold- or high-salinity- stress-inducible genes. However, we observed strong relationships in the expression of these stress-responsive genes based on Venn diagram analysis, and found 22 stress-inducible genes that responded to all three stresses. Several gene groups showing different expression profiles were identified by analysis of their expression patterns during stress-responsive gene induction. The cold-inducible genes were classified into at least two gene groups from their expression profiles. DREB1A was included in a group whose expression peaked at 2 h after cold treatment. Among the drought, cold or high-salinity stress-inducible genes identified, we found 40 transcription factor genes (corresponding to approximately 11% of all stress-inducible genes identified), suggesting that various transcriptional regulatory mechanisms function in the drought, cold or high-salinity stress signal transduction pathways.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / drug effects
  • Arabidopsis / genetics*
  • Cold Temperature*
  • Desiccation*
  • Disasters
  • Gene Expression Profiling*
  • Gene Expression Regulation, Plant / drug effects
  • Genes, Plant / genetics
  • Oligonucleotide Array Sequence Analysis*
  • Plant Diseases / chemically induced
  • Plant Diseases / genetics*
  • Promoter Regions, Genetic / genetics
  • RNA, Plant / analysis
  • RNA, Plant / genetics
  • Sodium Chloride / pharmacology*
  • Time Factors
  • Transcriptional Activation

Substances

  • RNA, Plant
  • Sodium Chloride