Cancer. DNA damage, deamidation, and death

Science. 2002 Nov 15;298(5597):1346-7. doi: 10.1126/science.1079168.
No abstract available

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • Apoptosis*
  • Asparagine / metabolism
  • Aspartic Acid / metabolism
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclins / metabolism
  • DNA Damage*
  • DNA, Neoplasm / drug effects
  • Genes, Retinoblastoma
  • Genes, p53
  • Humans
  • Models, Biological
  • Mutation
  • Neoplasms / drug therapy*
  • Neoplasms / metabolism
  • Neoplasms / pathology*
  • Protein Binding
  • Protein Structure, Tertiary
  • Proto-Oncogene Proteins c-bcl-2 / metabolism*
  • Retinoblastoma Protein / metabolism
  • Tumor Suppressor Protein p53 / metabolism
  • bcl-X Protein

Substances

  • Antineoplastic Agents
  • BCL2L1 protein, human
  • CDKN1A protein, human
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclins
  • DNA, Neoplasm
  • Proto-Oncogene Proteins c-bcl-2
  • Retinoblastoma Protein
  • Tumor Suppressor Protein p53
  • bcl-X Protein
  • Aspartic Acid
  • Asparagine