The non-invasive detection of intracranial aneurysms: are neuroradiologists any better than other observers?

Eur Radiol. 2003 Feb;13(2):389-96. doi: 10.1007/s00330-002-1520-1. Epub 2002 Jun 28.

Abstract

Can non-neuroradiologists detect intracranial aneurysms as well as neuroradiologists, using CT and MR angiography? Sixty patients undergoing intra-arterial digital subtraction angiography (IADSA) to detect aneurysms also underwent computed tomographic angiography (CTA) and time-of-flight magnetic resonance angiography (MRA). Consensus review of IADSA by two neuroradiologists was the reference standard. Two neuroradiologists, a neurosurgeon, a neuroradiographer and a general radiologist blinded to IADSA, plain CT and clinical data, independently reviewed hard-copy base and reconstructed maximum intensity projection images of the CTA and MRA studies. Thirty patients had a total of 63 aneurysms, 71.4% were </=5 mm in size. Compared with IADSA, mean accuracy per patient for neuroradiologists was CTA 0.87 (95% CI 0.75-0.94), and MRA 0.82 (0.70-0.90); for the other observers it was CTA 0.81 (0.75-0.86), and MRA 0.78 (0.71-0.84). Sensitivity per aneurysm for neuroradiologists was CTA 0.63 (0.50-0.75), and MRA 0.43 (0.6-0.74); for the other observers it was CTA 0.52 (0.44-0.59), and MRA 0.38 (0.31-0.45). Differences between readers and modalities were not statistically significant. Agreement with IADSA was "good" for neuroradiologists: kappa 0.73 for CTA, and 0.63 for MRA. For the other observers, agreement with IADSA was "moderate": kappa 0.59 for CTA, and 0.56 for MRA. Neuroradiologists performed consistently better than the other observers, although differences did not reach statistical significance.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Angiography, Digital Subtraction*
  • Cerebral Angiography*
  • Clinical Competence
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Intracranial Aneurysm / diagnosis*
  • Magnetic Resonance Angiography*
  • Male
  • Middle Aged
  • Neuroradiography*
  • Neurosurgery*
  • Observer Variation
  • Patient Care Team*
  • Prospective Studies
  • Reference Standards
  • Reproducibility of Results
  • Subarachnoid Hemorrhage / diagnosis
  • Tomography, Spiral Computed*