Gravitational effects on the response to different stimulatory signals in T cells

J Gravit Physiol. 2000 Jul;7(2):P9-11.

Abstract

The purpose of this paper is to present new data on the in vitro activation of purified T cells with three different mitogenic agents in conditions simulating low-gravity.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, CD / pharmacology*
  • CD28 Antigens / pharmacology
  • CD3 Complex / pharmacology
  • Cells, Cultured
  • Concanavalin A / pharmacology*
  • Gravitation
  • Humans
  • Interleukin-2 / pharmacology*
  • Lymphocyte Activation / drug effects
  • Lymphocyte Activation / physiology
  • Mitotic Index
  • Signal Transduction / drug effects
  • Signal Transduction / physiology
  • T-Lymphocytes / drug effects*
  • Weightlessness Simulation*

Substances

  • Antigens, CD
  • CD28 Antigens
  • CD3 Complex
  • Interleukin-2
  • Concanavalin A