Abstract
Most cases of serogroup C meningococcal disease are caused by the clonal lineages ST-8 and ST-11. The gene encoding the putative restriction-modification system NmeDI is specific to these lineages. We report here a monoclonal antibody directed against the NmeDI endonuclease as a tool for their rapid and spe-cific identification.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Monoclonal
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Antibody Specificity
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Bacterial Typing Techniques
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Carrier State / microbiology
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Humans
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Neisseria meningitidis / classification
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Neisseria meningitidis / immunology
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Neisseria meningitidis / isolation & purification
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Neisseria meningitidis / pathogenicity
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Restriction Mapping
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Virulence*