[Relationship between Helicobacter pylori negative chronic superficial gastritis and functional dyspepsia: are they the same disease?]

Zhonghua Nei Ke Za Zhi. 2003 Jul;42(7):476-8.
[Article in Chinese]

Abstract

Objective: To discriminate between Helicobacter pylori (Hp) negative chronic superficial gastritis and functional dyspepsia (FD) from therapeutic point of view.

Methods: 214 patients with Hp negative chronic superficial gastritis were randomly assigned into two groups. One group was case control trial group, another was cross-treated self-control group. Ordinary treatment of chronic gastritis (plan A) and FD plan (plan B) were given. Symptoms and pathologic changes were analysed and compared.

Results: In the case control group, the total effective rate of plan A and plan B was 89.2% and 88.5% respectively; in the cross-treated self-control group, the total effective rate of plan A and plan B was 81.8% and 89.8% respectively; There was no significant difference in the effective rate of the two different plans (P > 0.05).

Conclusions: Hp negative chronic superficial gastritis is similar to FD from therapeutic point of view. The method of treatment of the two diseases may be same, though they are named differently.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Case-Control Studies
  • Chronic Disease
  • Dyspepsia / drug therapy
  • Dyspepsia / etiology*
  • Female
  • Gastric Mucosa / pathology
  • Gastritis / complications*
  • Gastritis / drug therapy
  • Helicobacter Infections*
  • Helicobacter pylori*
  • Humans
  • Male
  • Middle Aged