Insights into Iberian population origins through the construction of highly informative Y-chromosome haplotypes using biallelic markers, STRs, and the MSY1 minisatellite

Am J Phys Anthropol. 2003 Oct;122(2):147-61. doi: 10.1002/ajpa.10231.

Abstract

To investigate the diversity of Y chromosomes in the Iberian Peninsula and the North African population of Maghreb, we constructed superhaplotypes on the basis of 10 biallelic markers, 7 microsatellites, and 1 minisatellite located in the nonrecombining portion of the human Y chromosome. The analysis of extremely high MSY1 variability was performed by reducing the MVR-codes to modular structures. Y-STRs and MSY1 data provide information about the relationship between closely related populations such as those of Iberia. Analysis of biallelic markers allowed us to identify 7 of 12 haplogroups defined by those polymorphisms. The haplogroup background showed clear differences between Iberian populations and the North African one. The use of differently mutating Y-chromosome markers allowed us to infer different population events at different time scales: the Paleolithic background of the Iberian Peninsula, the Neolithic fingerprint on Y-chromosome lineages, and the Iron Age influence in the populations of Iberia. Implications of our results for the highly debated origin of Basques are also discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Black People
  • Chromosomes, Human, Y*
  • Genetic Markers*
  • Genetics, Population*
  • Haplotypes
  • Humans
  • Minisatellite Repeats*
  • Polymorphism, Genetic
  • Spanien
  • White People

Substances

  • Genetic Markers