Abstract
We studied 60 patients with juvenile myoclonic epilepsy (JME). There was a high positive family history for epilepsy (33.3%). Age at onset of epilepsy ranged from 4 to 18 years with an average of 13.9 years. 88.3% of patients were seizure-free. The most effective drug was valproate. In eight patients drug withdrawal was attempted but all patients relapsed during a follow-up period of 1 year. Video-EEG studies were performed in eight newly diagnosed patients; myoclonic jerks were recorded in five patients.
MeSH terms
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Adolescent
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Adult
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Anticonvulsants / administration & dosage
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Cerebral Cortex / physiopathology
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Electroencephalography / drug effects
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Epilepsies, Myoclonic / diagnosis*
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Epilepsies, Myoclonic / genetics
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Epilepsies, Myoclonic / physiopathology
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Epilepsy, Absence / diagnosis
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Epilepsy, Absence / genetics
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Epilepsy, Absence / physiopathology
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Epilepsy, Tonic-Clonic / diagnosis
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Epilepsy, Tonic-Clonic / genetics
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Epilepsy, Tonic-Clonic / physiopathology
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Evoked Potentials / drug effects
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Evoked Potentials / physiology
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Female
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Follow-Up Studies
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Functional Laterality / physiology
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Humans
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Male
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Middle Aged
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Photic Stimulation
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Polysomnography
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Video Recording