Abstract
A total of 10 desmoplastic small round-cell tumour patients were treated by high-dose chemotherapy with stem cell support. After high-dose chemotherapy, no complete response conversion was obtained and EWS-WT1 fusion transcript detection was positive in the peripheral blood during follow-up in all patients. High-dose chemotherapy did not seem to change the results in desmoplastic small round-cell tumour.
MeSH terms
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Abdominal Neoplasms / genetics
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Abdominal Neoplasms / therapy*
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Adolescent
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Adult
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Carcinoma, Small Cell / genetics
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Carcinoma, Small Cell / therapy*
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Combined Modality Therapy
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DNA Primers / chemistry
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Humans
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Male
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Middle Aged
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Oncogene Proteins, Fusion / genetics
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Oncogene Proteins, Fusion / metabolism
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Peripheral Blood Stem Cell Transplantation*
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Prognosis
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Prospective Studies
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Reverse Transcriptase Polymerase Chain Reaction
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Survival Rate
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Transplantation, Autologous
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Treatment Outcome
Substances
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DNA Primers
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EWS1-WT1 fusion protein, human
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Oncogene Proteins, Fusion