Infections in international pregnancy study: performance of the optical immunoassay test for detection of group B streptococcus

Jadsada Thinkhamrop; Sompop Limpongsanurak; Mario R Festin; Sean Daly; Anne Schuchat; Pisake Lumbiganon; Elizabeth Zell; Tsungai Chipato; Aye Aye Win; Mindy J Perilla; Jorge E Tolosa; Cynthia G Whitney

doi:10.1128/JCM.41.11.5288-5290.2003

Infections in international pregnancy study: performance of the optical immunoassay test for detection of group B streptococcus

J Clin Microbiol. 2003 Nov;41(11):5288-90. doi: 10.1128/JCM.41.11.5288-5290.2003.

Authors

Jadsada Thinkhamrop¹, Sompop Limpongsanurak, Mario R Festin, Sean Daly, Anne Schuchat, Pisake Lumbiganon, Elizabeth Zell, Tsungai Chipato, Aye Aye Win, Mindy J Perilla, Jorge E Tolosa, Cynthia G Whitney

Affiliation

¹ Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Bangkok, Thailand. [email protected]

Abstract

We evaluated the Strep B optical immunoassay (OIA; ThermoBiostar, Inc.) for detecting light and heavy group B streptococcus colonization in 1,306 pregnant women. The women were examined at 20 to 32 weeks gestation and were from six countries. Compared to culture, the sensitivity and specificity of OIA were 13.3 and 98.4%, respectively, for light colonization and 41.5 and 97.7%, respectively, for heavy colonization.

Publication types

Comparative Study

MeSH terms

Female
Humans
Immunoassay / methods
Ireland / epidemiology
Myanmar / epidemiology
Philadelphia / epidemiology
Philippines / epidemiology
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Pregnancy Complications, Infectious / epidemiology
Prevalence
Streptococcal Infections / diagnosis
Streptococcal Infections / epidemiology*
Streptococcus agalactiae / isolation & purification*
Zimbabwe / epidemiology