Leiocyclocin C and D, two cyclopeptides from Goniothalamus leiocarpus

Pharmazie. 2003 Oct;58(10):756-8.

Abstract

Two new cyclopeptides, leiocyclocin C (1) and D (2), were isolated from the seeds of Goniothalamus leiocarpus (Annonaceae). Their structures were determined as cyclo-(Gly1-Ser-Pro2-Tyr2-Gly2-Tyr1-Pro1-Pro3) and cyclo-(Gly1-Leu-Pro1-Gly2-Phe-Tyr-Pro2), respectively, by means of spectral and chemical methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Annonaceae / chemistry*
  • Magnetic Resonance Spectroscopy
  • Peptides, Cyclic / chemistry*
  • Plant Extracts / analysis
  • Spectrometry, Mass, Fast Atom Bombardment

Substances

  • Peptides, Cyclic
  • Plant Extracts
  • leiocyclocin C
  • leiocyclocin D