Metastatic gastrointestinal stromal tumor with an exon 11 c-kit mutation responding to the tyrosine kinase inhibitor imatinib

Dig Surg. 2004;21(1):74-7. doi: 10.1159/000076756. Epub 2004 Feb 12.

Authors

Haruhiko Cho¹, Osamu Kobayashi, Akira Tsuburaya, Yuka Sugiyama, Motonori Sairenji, Hisahiko Motohashi, Tsutomu Yoshida, Yohei Miyagi, Toshio Imada

Affiliation

¹ Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan. [email protected]

PMID: 14967957
DOI: 10.1159/000076756

No abstract available

Publication types

Case Reports

MeSH terms

Benzamides
Exons / genetics
Female
Gastrointestinal Neoplasms / drug therapy*
Gastrointestinal Neoplasms / genetics*
Gastrointestinal Neoplasms / pathology
Humans
Imatinib Mesylate
Immunohistochemistry
Middle Aged
Mutation
Neoplasm Invasiveness
Piperazines / therapeutic use*
Protein-Tyrosine Kinases / antagonists & inhibitors*
Proto-Oncogene Proteins c-kit / metabolism*
Pyrimidines / therapeutic use*
Remission Induction
Stromal Cells

Substances

Benzamides
Piperazines
Pyrimidines
Imatinib Mesylate
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-kit