Possible contribution of C-reactive protein within coronary plaque to increasing its own plasma levels across coronary circulation

Tetsunori Ishikawa; Takuroh Imamura; Kinta Hatakeyama; Haruhiko Date; Toshiro Nagoshi; Riichirou Kawamoto; Akihiko Matsuyama; Yujiro Asada; Tanenao Eto

doi:10.1016/j.amjcard.2003.11.030

Possible contribution of C-reactive protein within coronary plaque to increasing its own plasma levels across coronary circulation

Am J Cardiol. 2004 Mar 1;93(5):611-4. doi: 10.1016/j.amjcard.2003.11.030.

Authors

Tetsunori Ishikawa¹, Takuroh Imamura, Kinta Hatakeyama, Haruhiko Date, Toshiro Nagoshi, Riichirou Kawamoto, Akihiko Matsuyama, Yujiro Asada, Tanenao Eto

Affiliation

¹ First Department of Internal Medicine, Miyazaki Medical College, Kiyotake, Miyazaki, Japan.

PMID: 14996590
DOI: 10.1016/j.amjcard.2003.11.030

Abstract

C-reactive protein (CRP) mRNA was detected in coronary plaque. Plasma CRP levels across the coronary circulation were increased much more in patients with unstable angina pectoris and somewhat more in those with stable angina pectoris compared with controls whose coronary arteries were angiographically normal. Thus, CRP within coronary plaque might contribute to increased plasma CRP levels across coronary circulation, particularly among patients with unstable angina pectoris.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Angina, Unstable / blood*
Angina, Unstable / etiology
Angina, Unstable / surgery
Atherectomy, Coronary
C-Reactive Protein / genetics
C-Reactive Protein / metabolism*
Coronary Artery Disease / complications
Coronary Artery Disease / metabolism*
Coronary Artery Disease / surgery*
Coronary Vessels / metabolism*
Coronary Vessels / surgery*
Female
Humans
Male
Middle Aged
RNA, Messenger / genetics

Substances

RNA, Messenger
C-Reactive Protein