Subcutaneous infection with Mycobacterium abscessus in a renal transplant recipient

Dermatology. 2004;208(3):259-61. doi: 10.1159/000077314.

Abstract

Transplant recipients show a high incidence of infections, often with atypical manifestations mainly because of drug-related immunosuppression. Mycobacterial infections can be life-threatening in immunosuppressed patients due to the risk of dissemination. There have been only few reports of cutaneous infections with Mycobacterium abscessus among immunosuppressed patients. We present a rare case with a sporotrichoid skin infection with M. abscessus in a renal recipient. The value of immunohistochemical detection of mycobacteria using an anti-BCG antibody in the diagnostic work-up skin biopsies is demonstrated. Long-term antibiotic treatment resulted in complete remission, although recurrences with atypical presentation were observed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Female
  • Humans
  • Immunocompromised Host*
  • Kidney Transplantation / immunology*
  • Mycobacterium Infections / diagnosis*
  • Mycobacterium Infections / drug therapy
  • Skin Diseases, Bacterial / diagnosis*
  • Skin Diseases, Bacterial / microbiology

Substances

  • Anti-Bacterial Agents
  • Clarithromycin