Tuberculosis in renal transplants in Rio de Janeiro

Transplant Proc. 2004 May;36(4):905-6. doi: 10.1016/j.transproceed.2004.03.093.

Abstract

Retrospective analysis of 982 renal transplants over 21 years (1981 to 2002) sought to evaluate the prevalence of tuberculosis (TB). This analysis included 74 patients: 30 with a past TB history, who had INH prophylaxis since the beginning of immunosuppression, and 44 who only became TB infected after receiving transplants. The diagnosis of TB was made by a compatible medical situation with bacteriological/histological confirmation, which when not possible, underwent a therapeutic test occur. The average time for the illness to surge was 3 years. The mortality rate was 34.9% (15/44). Patients with hepatitis C were more affected. Among those who used INH prophylaxis only one contracted TB, showing that the drug displayed a protection rate of 96.6% (29/30).

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Brazil / epidemiology
  • Follow-Up Studies
  • Humans
  • Kidney Transplantation / adverse effects*
  • Retrospective Studies
  • Time Factors
  • Tuberculosis / drug therapy
  • Tuberculosis / epidemiology*
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / epidemiology

Substances

  • Antitubercular Agents