Abstract
We report a case of maternal anaphylaxis following intrapartum chemoprophylaxis. The term fetus developed severe brain damage as a consequence of intrapartum asphyxia. The lesions resulted from maternal hypotension following anaphylaxis. We discuss the feto-maternal risks and the controversial treatment of such a condition. The increasing number of penicillin-treated parturients will result in further cases of maternal anaphylaxis than previously found.
MeSH terms
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Adult
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Ampicillin / administration & dosage
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Ampicillin / adverse effects*
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Anaphylaxis / chemically induced*
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / adverse effects*
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Asphyxia Neonatorum / diagnosis
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Asphyxia Neonatorum / etiology
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Brain Damage, Chronic / diagnosis*
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Brain Damage, Chronic / diagnostic imaging
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Brain Damage, Chronic / etiology
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Brain Damage, Chronic / pathology
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Diagnosis, Differential
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Female
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Fetal Membranes, Premature Rupture*
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Humans
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Infant, Newborn
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Infusions, Intravenous
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Magnetic Resonance Imaging
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Pregnancy
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Pregnancy Trimester, Third
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Ultrasonography
Substances
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Anti-Bacterial Agents
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Ampicillin