Abstract
Intravascular lymphoma is an uncommon and often overlooked form of non-Hodgkin's lymphoma characterized by extensive proliferation of lymphoid cells within the lumina of small and medium-sized vessels. Clinical symptoms of the disease are variable and often nonspecific, mostly neurologic in nature. With an aggressive course, intravascular lymphomatosis has a poor prognosis and is rarely diagnosed ante mortem. We describe here a 76-year-old woman with the clinical diagnoses of hemolytic anemia and progressive lethargy where intravascular lymphomatosis turned out as the underlying cause of the disease.
MeSH terms
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Aged
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Anemia, Hemolytic / etiology*
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Biomarkers, Tumor / blood
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Diagnosis, Differential
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Disease Progression
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Fatal Outcome
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Fatigue / etiology*
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Female
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Headache / etiology
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Humans
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L-Lactate Dehydrogenase / blood
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Lymphoma, Large B-Cell, Diffuse / blood
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Lymphoma, Large B-Cell, Diffuse / complications
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Lymphoma, Large B-Cell, Diffuse / diagnosis*
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Lymphoma, Large B-Cell, Diffuse / pathology
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Multiple Organ Failure / etiology
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Purpura, Thrombotic Thrombocytopenic / diagnosis
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Sleep Stages
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Uric Acid / blood
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Vascular Neoplasms / blood
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Vascular Neoplasms / complications
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Vascular Neoplasms / diagnosis*
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Vascular Neoplasms / pathology
Substances
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Biomarkers, Tumor
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Uric Acid
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L-Lactate Dehydrogenase