Montelukast and airway remodeling in children with chronic persistent asthma: an open study

Pediatr Allergy Immunol. 2004 Oct;15(5):472-3. doi: 10.1111/j.1399-3038.2004.00184.x.

Abstract

We report a 4 yr follow up study of seven asthmatic children with chronic persistent asthma, high-residual volume and low-density areas at high-resolution computerized tomography after treatment with salmeterol and fluticasone. Improvement of lung function with disappearance of low-density areas in six patients after treatment with fluticasone and montelukast was obtained.

Publication types

  • Clinical Trial

MeSH terms

  • Acetates / therapeutic use*
  • Albuterol / analogs & derivatives*
  • Albuterol / therapeutic use
  • Androstadienes / therapeutic use
  • Anti-Asthmatic Agents / therapeutic use*
  • Asthma / drug therapy*
  • Bronchodilator Agents / therapeutic use
  • Child
  • Chronic Disease
  • Cyclopropanes
  • Drug Therapy, Combination
  • Fluticasone
  • Follow-Up Studies
  • Humans
  • Lung / drug effects*
  • Quinolines / therapeutic use*
  • Respiratory Function Tests
  • Salmeterol Xinafoate
  • Sulfides

Substances

  • Acetates
  • Androstadienes
  • Anti-Asthmatic Agents
  • Bronchodilator Agents
  • Cyclopropanes
  • Quinolines
  • Sulfides
  • Salmeterol Xinafoate
  • Fluticasone
  • montelukast
  • Albuterol