[Venous thromboembolism in patients with neurosurgical process or stroke. A prospective analysis from the RIETE registry]

Med Clin (Barc). 2004 Oct 2;123(11):416-8. doi: 10.1016/s0025-7753(04)74537-6.
[Article in Spanish]

Abstract

Background and objective: We studied the characteristics of thromboembolic disease in patients who have suffered a deep venous thrombosis or a pulmonary thromboembolism with the occurrence, two months before, of a neurosurgical process or a stroke.

Patients and method: We analyzed the variables of 57 patients who underwent a neurosurgical operation and those of 86 patients who suffered a stroke. These variables were included in the Computerised Records of Thromboembolic Disease.

Results: The average age was of 62.3 (1.9) for neurosurgical and 71.7 (1.5) for stroke patients (p < 0.001). Prophylaxis was previously applied to 31.6% of neurosurgical patients and to 37.2% of patients in the stroke group. Most patients were treated with low molecular weight heparin during the acute phase of the illness. In both groups, 50% of deaths was associated with thromboembolic disease. The proportion of deceases was related to the associated disease and it was significantly higher in the stroke group (18% versus 4.2% in the neurosurgical group, p = 0.028).

Conclusions: In our study, thromboembolic disease was responsible of 50% of deaths. Stroke patients make up a group with a bad prognosis due to their older age and higher frequency of associated pathology; they have a higher risk of death.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anticoagulants / therapeutic use
  • Female
  • Heparin, Low-Molecular-Weight / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Neurosurgical Procedures / mortality*
  • Postoperative Complications / mortality
  • Postoperative Complications / prevention & control
  • Prognosis
  • Pulmonary Embolism / mortality
  • Pulmonary Embolism / prevention & control*
  • Registries
  • Risk Factors
  • Stroke / mortality*
  • Venous Thrombosis / mortality
  • Venous Thrombosis / prevention & control*

Substances

  • Anticoagulants
  • Heparin, Low-Molecular-Weight