Correlation of ERK-phosphorylation and toxicities in patients treated with the Raf kinase inhibitor BAY 43-9006

Int J Clin Pharmacol Ther. 2004 Nov;42(11):648-9. doi: 10.5414/cpp42648.
No abstract available

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Area Under Curve
  • Benzenesulfonates / administration & dosage
  • Benzenesulfonates / adverse effects
  • Benzenesulfonates / pharmacology*
  • Diarrhea / chemically induced
  • Drug Administration Schedule
  • Exanthema / chemically induced
  • Humans
  • Neoplasms / drug therapy*
  • Niacinamide / analogs & derivatives
  • Phenylurea Compounds
  • Phosphorylation / drug effects
  • Proto-Oncogene Proteins c-raf / antagonists & inhibitors*
  • Pyridines / administration & dosage
  • Pyridines / adverse effects
  • Pyridines / pharmacology*
  • Sorafenib

Substances

  • Benzenesulfonates
  • Phenylurea Compounds
  • Pyridines
  • Niacinamide
  • Sorafenib
  • Proto-Oncogene Proteins c-raf