ProfDist: a tool for the construction of large phylogenetic trees based on profile distances

Joachim Friedrich; Thomas Dandekar; Matthias Wolf; Tobias Müller

doi:10.1093/bioinformatics/bti289

ProfDist: a tool for the construction of large phylogenetic trees based on profile distances

Bioinformatics. 2005 May 1;21(9):2108-9. doi: 10.1093/bioinformatics/bti289. Epub 2005 Jan 27.

Authors

Joachim Friedrich¹, Thomas Dandekar, Matthias Wolf, Tobias Müller

Affiliation

¹ Department of Bioinformatics, Biocenter, University of Würzburg, Germany.

PMID: 15677706
DOI: 10.1093/bioinformatics/bti289

Abstract

Summary: ProfDist is a user-friendly software package using the profile-neighbor-joining method (PNJ) in inferring phylogenies based on profile distances on DNA or RNA sequences. It is a tool for reconstructing and visualizing large phylogenetic trees providing new and standard features with a special focus on time efficency, robustness and accuracy.

Availability: A Windows version of ProfDist comes with a graphical user interface and is freely available at http://profdist.bioapps.biozentrum.uni-wuerzburg.de

MeSH terms

Algorithms*
Chromosome Mapping / methods*
DNA Mutational Analysis / methods
Gene Expression Profiling / methods*
Linkage Disequilibrium / genetics*
Phylogeny*
Sequence Alignment / methods
Sequence Analysis, DNA / methods*
Software*
User-Computer Interface*