Effects of Ginkgo biloba on haemostatic factors and inflammation in chronic peritoneal dialysis patients

Phytother Res. 2005 Jun;19(6):546-8. doi: 10.1002/ptr.1633.

Abstract

Ginkgo biloba extract decreased plasma D-dimer concentration, a marker of intravascular coagulation, in chronic peritoneal dialysis patients. Blood levels of fibrinogen, von Willebrand factor, hs-CRP, albumin and liver enzyme levels were not significantly changed. No bleeding episode was reported. These results suggest that Ginkgo biloba extract was effective in partially reversing the thrombogenic coagulation profile without increasing the risk of bleeding.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / pharmacology*
  • Anti-Inflammatory Agents / therapeutic use
  • Anticoagulants / administration & dosage
  • Anticoagulants / pharmacology*
  • Anticoagulants / therapeutic use
  • Blood Coagulation Factors / drug effects
  • Female
  • Ginkgo biloba*
  • Humans
  • Kidney Failure, Chronic / therapy
  • Male
  • Middle Aged
  • Peritoneal Dialysis, Continuous Ambulatory
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Anticoagulants
  • Blood Coagulation Factors
  • Plant Extracts