Conjugation of 3' hexameric deoxyriboguanosine run to phosphodiester CpG oligodeoxynucleotides can inhibit allergen-specific IgE synthesis with less risk of splenomegaly

J Allergy Clin Immunol. 2005 Dec;116(6):1388-90. doi: 10.1016/j.jaci.2005.09.022. Epub 2005 Nov 2.

Authors

Yoon-Seok Chang, Yoon-Keun Kim, Kyung-Up Min, You-Young Kim, Young Chul Seong, Sang-Heon Cho

PMID: 16337478
DOI: 10.1016/j.jaci.2005.09.022

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Allergens / immunology*
Animals
Immunoglobulin E / biosynthesis*
Mice
Mice, Inbred BALB C
Oligodeoxyribonucleotides / adverse effects*
Oligodeoxyribonucleotides / pharmacology
Splenomegaly / prevention & control*

Substances

Allergens
CPG-oligonucleotide
Oligodeoxyribonucleotides
Immunoglobulin E