Abstract
Four new chromones, perforamone A, B, C, and D have been isolated together with six known compounds, peucenin-7-methyl ether, O-methylalloptaeroxylin, perforatic acid, eugenin, saikochromone A and greveichromenol, from the branches of Harrisonia perforata (Simaroubaceae). The structures were identified by spectroscopic data. The compounds were tested for antimycobacterial and antiplasmodial activities.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antimalarials / chemistry
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Antimalarials / pharmacology
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Antitubercular Agents / chemistry
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Antitubercular Agents / pharmacology
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Chromatography, Thin Layer
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Chromones / chemistry*
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Chromones / isolation & purification
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Chromones / pharmacology*
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Magnetic Resonance Spectroscopy
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Mycobacterium tuberculosis
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Plasmodium falciparum / drug effects
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Simaroubaceae / chemistry*
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
Substances
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Antimalarials
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Antitubercular Agents
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Chromones