Randomised controlled trial of combined paracetamol and ibuprofen for fever

M D S Erlewyn-Lajeunesse; K Coppens; L P Hunt; P J Chinnick; P Davies; I M Higginson; J R Benger

doi:10.1136/adc.2005.087874

Randomised controlled trial of combined paracetamol and ibuprofen for fever

Arch Dis Child. 2006 May;91(5):414-6. doi: 10.1136/adc.2005.087874. Epub 2006 Feb 7.

Authors

M D S Erlewyn-Lajeunesse¹, K Coppens, L P Hunt, P J Chinnick, P Davies, I M Higginson, J R Benger

Affiliation

¹ Clinical Sciences at South Bristol, Faculty of Medicine, University of Bristol, UK. [email protected]

Abstract

A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.

Publication types

Randomized Controlled Trial

MeSH terms

Acetaminophen / therapeutic use*
Analgesics, Non-Narcotic / therapeutic use*
Child
Child, Preschool
Drug Therapy, Combination
Emergencies
Female
Fever / drug therapy*
Humans
Ibuprofen / therapeutic use*
Infant
Male
Time Factors
Treatment Outcome

Substances

Analgesics, Non-Narcotic
Acetaminophen
Ibuprofen