We experienced the anesthetic management of a child with epidermolysis bullosa undergoing esophageal dilatation. Anesthesia was induced with oxygen/nitrous oxide mixture and sevoflurane. Oral tracheal intubation was with a lubricated laryngoscope blade using vecuronium 0.1 mg x kg(-1) and fentanyl 0.1 microg x kg(-1). To avoid friction and shearing forces on the skin, endotracheal tube was tied with a tape without adhesion and fixed around the neck. We removed adhesive parts of pulse-oximetry probe and electrocardiogram electrodes, then attached to the patient's skin covered with Vaseline. Peripheral venous access was secured in the left ankle and sutured. These methods were effective to avoid new blisters and to keep patient safe.