Recurrent mesenchymal hamartoma associated with 19q translocation. A call for more radical surgical resection

Eur J Pediatr Surg. 2006 Feb;16(1):64-7. doi: 10.1055/s-2005-873072.

Abstract

Hepatic mesenchymal hamartoma is a rare benign tumour in children. It is often large and centrally located in the liver at diagnosis, making surgical resection difficult; thus non-radical resection has been proposed in the past as acceptable management. However, a literature survey and a case with recurrence associated with cytogenetic anomalies suggest that radical liver surgery (resection with a margin of normal liver parenchyma, as for malignant tumour) should be recommended for mesenchymal hamartoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Chromosomes, Human, Pair 19 / genetics*
  • Female
  • Hamartoma / genetics*
  • Hamartoma / pathology
  • Hamartoma / surgery
  • Hepatectomy
  • Humans
  • Infant
  • Liver Neoplasms / genetics*
  • Liver Neoplasms / pathology
  • Liver Neoplasms / surgery
  • Mesoderm / pathology
  • Neoplasm Recurrence, Local / genetics*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery
  • Translocation, Genetic*