Two new alkaloidal taxoids from the needles of Taxus canadensis

Biosci Biotechnol Biochem. 2006 Mar;70(3):732-6. doi: 10.1271/bbb.70.732.

Abstract

Two new taxanes with a dimethylamino group on the C-5 side chain were identified for the first time in the needles of the Canadian yew, Taxus canadensis. Their structures were characterized as 7beta,10beta,13alpha-triacetoxy-5alpha-(3'-dimethylamino-3'-phenylpropanoyl)oxy-2alpha-hydroxy-2(3-->20)abeotaxa-4(20),11-dien-9-one (1) and 2alpha,10beta-diacetoxy-9alpha-hydroxy-5alpha-(3'-dimethylamino-3'-phenylpropanoyl)oxy-3,11-cyclotax-4(20)-en-13-one (2).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry*
  • Alkaloids / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Taxoids / chemistry*
  • Taxoids / isolation & purification*
  • Taxus / chemistry*

Substances

  • Alkaloids
  • Taxoids