Relationship between Helicobacter pylori infection and Alzheimer disease

Neurology. 2006 Mar 28;66(6):938-40. doi: 10.1212/01.wnl.0000203644.68059.5f.

Abstract

The authors investigated the association between Helicobacter pylori infection (Hp-I) and Alzheimer disease (AD) by using histology for diagnosis of Hp-I. Fifty patients with AD and 30 iron deficiency anemic control participants without AD were included. The histologic prevalence of Hp-I was 88% in patients with AD and 46.7% in controls (p < 0.001).

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / epidemiology*
  • Alzheimer Disease / etiology
  • Alzheimer Disease / pathology*
  • Female
  • Gastric Mucosa / pathology
  • Gastroscopy / standards
  • Helicobacter Infections / complications
  • Helicobacter Infections / epidemiology*
  • Helicobacter Infections / pathology*
  • Helicobacter pylori*
  • Humans
  • Male
  • Middle Aged