[A rare cause of a central bile duct stricture]

Dtsch Med Wochenschr. 2006 Apr 28;131(17):973-6. doi: 10.1055/s-2006-939878.
[Article in German]

Abstract

History and clinical findings: A 55 year old female patient was diagnosed because of painless jaundice and weight loss. She had undergone conventional cholecystectomy 15 years before.

Investigations: Bilirubin level before ERCP and stent implantation was 287 micromol/l at maximum. A subtotal stenosis was found in the proximal common hepatic duct. Endosonographically, a mass of 14 mm diameter was seen. She was suspected of having a Klatskin tumour Bismuth type II. Tumour markers (CEA, CA19-9) were within normal ranges.

Treatment and course: One month after stent implantation open surgery was performed suspecting a malignant tumour of the bile duct. A solid tumour at the hepatic bifurcation was resected completely. Reconstruction was performed by hepatico-jejunostomy was formed and the blind end of the jejunum was anastomosed to the gastric antrum to form an "access loop". Upon histological analysis no malignancy was found. However, a distinct fibrosis within the suspicious area was seen, formed around braided suture material.

Conclusion: Preoperative distinction between benign and malignant bile duct stenosis can be difficult, even impossible. Thus, every resectable bile duct tumour should undergo surgery even and especially if a histological diagnosis cannot be reached preoperatively and the condition of the patient is adequate.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anastomosis, Surgical / methods
  • Bile Duct Neoplasms / diagnosis
  • Bile Duct Neoplasms / pathology
  • Bilirubin / blood
  • Cholecystectomy
  • Cholestasis / etiology*
  • Cholestasis / pathology
  • Cholestasis / surgery*
  • Common Bile Duct / pathology*
  • Common Bile Duct / surgery*
  • Diagnosis, Differential
  • Female
  • Fibrosis
  • Hepatic Duct, Common
  • Humans
  • Jaundice
  • Jejunum / surgery
  • Klatskin Tumor / diagnosis
  • Klatskin Tumor / pathology
  • Middle Aged
  • Pyloric Antrum / surgery
  • Stents*
  • Treatment Outcome
  • Weight Loss

Substances

  • Bilirubin