Abstract
The synthesis and P2Y2 activities of a novel series of nucleoside triphosphates are described. Many of these compounds were potent agonists of the P2Y2 receptor.
MeSH terms
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Cell Line, Tumor
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DNA, Complementary / biosynthesis
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DNA, Complementary / genetics
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Humans
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Indicators and Reagents
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Magnetic Resonance Spectroscopy
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Nucleotides / chemical synthesis*
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Nucleotides / pharmacology*
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Purinergic P2 Receptor Agonists*
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Receptors, Purinergic P2Y2
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Reverse Transcriptase Polymerase Chain Reaction
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Structure-Activity Relationship
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Uridine Triphosphate / pharmacology
Substances
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DNA, Complementary
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Indicators and Reagents
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Nucleotides
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P2RY2 protein, human
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Purinergic P2 Receptor Agonists
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Receptors, Purinergic P2Y2
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Uridine Triphosphate