Cytomegalovirus pneumonia after stem cell transplantation: correlation of CT findings with clinical outcome in 30 patients

AJR Am J Roentgenol. 2006 Dec;187(6):W636-43. doi: 10.2214/AJR.04.1592.

Abstract

Objective: The purpose of our study was to assess the correlation between early high-resolution CT findings of cytomegalovirus (CMV) pneumonia in patients with blood disorders and their clinical outcomes.

Conclusion: The initial high-resolution CT findings in immunocompromised patients with CMV pneumonia seem to predict the patient's outcome being unfavorable in those forms of disease beginning mostly bilaterally as diffuse or patchy ground-glass opacity followed by progressive air-space consolidation. Also, a change in the CT morphology of pulmonary lesions toward diffuse ground-glass opacity seems to correlate with an unfavorable disease course.

MeSH terms

  • Adult
  • Cytomegalovirus Infections / diagnostic imaging*
  • Cytomegalovirus Infections / etiology*
  • Female
  • Hematologic Neoplasms / therapy
  • Humans
  • Immunocompromised Host
  • Male
  • Middle Aged
  • Pneumonia / diagnostic imaging*
  • Pneumonia / etiology
  • Pneumonia / virology*
  • Prognosis
  • Radiography
  • Retrospective Studies
  • Risk Factors
  • Stem Cell Transplantation / adverse effects*
  • Treatment Outcome