Abstract
In this cross-sectional multicenter study, we determined the rate of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in children admitted to 9 training hospitals in Switzerland during 1 month. From 1337 patients, 1363 nasal swabs were obtained (mean age 6.1 years, median 4.7 years, interquartile range 1.3-10.4 years) and 562 (41.3%) grew S. aureus. Only one isolate was MRSA (0.18%) which encoded mecA and femA genes as well as SCCmec type IV, whereas Panton-Valentine leukocidin (PVL) was absent.
Publication types
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Multicenter Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Bacterial Proteins / genetics
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Bacterial Toxins / genetics
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Carrier State / epidemiology*
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Carrier State / microbiology*
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Child
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Child, Preschool
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Cross-Sectional Studies
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DNA, Bacterial / genetics
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Exotoxins / genetics
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Female
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Hospitalization
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Hospitals, Teaching
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Humans
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Infant
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Leukocidins / genetics
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Male
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Methicillin Resistance*
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Nasal Cavity / microbiology*
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Penicillin-Binding Proteins
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Prevalence
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Staphylococcal Infections / epidemiology*
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Staphylococcal Infections / microbiology*
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / isolation & purification*
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Switzerland / epidemiology
Substances
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Bacterial Proteins
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Bacterial Toxins
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DNA, Bacterial
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Exotoxins
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FemA protein, Bacteria
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Leukocidins
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Panton-Valentine leukocidin
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Penicillin-Binding Proteins
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mecA protein, Staphylococcus aureus