Myasthenia gravis with concomitant severe paraspinal muscle degeneration and mitochondrial DNA4977 deletion

Nobuo Wakata; Shinngo Konno; Nobuatsu Nomoto; Hideki Sugimoto; Hiroshi Nemoto; Teruyuki Kurihara; Masahiko Kishi

doi:10.2169/internalmedicine.46.6400

Myasthenia gravis with concomitant severe paraspinal muscle degeneration and mitochondrial DNA4977 deletion

Intern Med. 2007;46(11):747-50. doi: 10.2169/internalmedicine.46.6400. Epub 2007 Jun 1.

Authors

Nobuo Wakata¹, Shinngo Konno, Nobuatsu Nomoto, Hideki Sugimoto, Hiroshi Nemoto, Teruyuki Kurihara, Masahiko Kishi

Affiliation

¹ Department of Neurology, Toho University, Oohashi Hospital, Tokyo. [email protected]

PMID: 17541228
DOI: 10.2169/internalmedicine.46.6400

Abstract

Recent reports have discussed the many causes of dropped head syndrome and bent spine syndrome. We described a case of myasthenia gravis with concomitant severe degeneration of spinal muscle, mitochondrial DNA4977 deletion and sensorineural deafness. These associations were thought to be independent, however this is an important case to consider the etiology of bent spine syndrome.

Publication types

Case Reports

MeSH terms

DNA, Mitochondrial / genetics*
Female
Gene Deletion*
Hearing Loss, Sensorineural / diagnosis
Hearing Loss, Sensorineural / etiology
Humans
Magnetic Resonance Imaging
Middle Aged
Muscle, Skeletal / pathology
Muscular Atrophy / etiology*
Muscular Atrophy / pathology
Myasthenia Gravis / complications*
Myasthenia Gravis / diagnosis
Myasthenia Gravis / genetics*
Spinal Curvatures / etiology*
Spinal Curvatures / pathology
Syndrome

Substances

DNA, Mitochondrial