[R1 resection in the surgery of upper gastrointestinal tumors: relevance and therapeutic consequences]

Chirurg. 2007 Sep;78(9):792-801. doi: 10.1007/s00104-007-1381-x.
[Article in German]

Abstract

Microscopically involved tumor margins are an important problem in the surgery of locally advanced esophageal and gastric carcinomas. We conducted a systematic review of the literature and a specific analysis of our own patient database. This article summarizes current knowledge of the incidence and prognosis of R1 resections in upper gastrointestinal cancers. Preoperative strategies for reducing the rate of R1 resections are presented, and the surgical options in case of R1 resection are discussed.

Publication types

  • Comparative Study
  • Review
  • Systematic Review

MeSH terms

  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / mortality
  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery*
  • Endosonography
  • Esophageal Neoplasms / diagnostic imaging
  • Esophageal Neoplasms / mortality
  • Esophageal Neoplasms / pathology
  • Esophageal Neoplasms / surgery*
  • Esophagus / pathology
  • Gastrectomy
  • Humans
  • Kaplan-Meier Estimate
  • Multicenter Studies as Topic
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Neoplasm, Residual / diagnosis
  • Neoplasm, Residual / diagnostic imaging
  • Neoplasm, Residual / pathology
  • Neoplasm, Residual / surgery*
  • Prognosis
  • Stomach / pathology
  • Stomach Neoplasms / diagnostic imaging
  • Stomach Neoplasms / mortality
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / surgery*
  • Time Factors