Haemorrhagic presentation of low-grade glioma in adults

Acta Neurochir (Wien). 2007 Nov;149(11):1151-5; discussion 1155. doi: 10.1007/s00701-007-1263-5. Epub 2007 Aug 6.

Abstract

Intracranial bleeding is rare in patients with low-grade gliomas, above all in adult population. We reviewed the literature of such cases and reported another case of a haemorrhagic low-grade glioma in a 54-year-old woman presenting with a left hemiparesis. Computer tomography (CT) images showed a right basal ganglia haemorrhage with no mass effect. Vascular malformations were ruled out by angiography. Eighteen fluoro-fluoro deossiglucosio (18F-FDG) positron emission tomography (PET/CT) showed a large hypometabolic area corresponding to the lesion. We waited for patient's improvement. Late magnetic resonance images revealed a low-grade glioma at the bleeding site. Tumour was removed and histopathologic examination revealed a WHO grade II mixed glioma. The authors emphasize that this evidence has to be kept in mind since it has important therapeutic implications.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Astrocytoma / diagnosis*
  • Astrocytoma / pathology
  • Astrocytoma / surgery
  • Basal Ganglia Diseases / diagnosis*
  • Basal Ganglia Diseases / pathology
  • Basal Ganglia Diseases / surgery
  • Basal Ganglia Hemorrhage / diagnosis
  • Basal Ganglia Hemorrhage / etiology*
  • Basal Ganglia Hemorrhage / pathology
  • Basal Ganglia Hemorrhage / surgery
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Craniotomy
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Neuronavigation
  • Positron-Emission Tomography*
  • Putaminal Hemorrhage / diagnosis
  • Putaminal Hemorrhage / etiology*
  • Putaminal Hemorrhage / pathology
  • Putaminal Hemorrhage / surgery
  • Tomography, X-Ray Computed*